TRPA1 Activation by Allyl Isothiocyanate

This application note presents data recorded on the Port-a- Patch® with external perfusion showing recordings of human TRPA1 (hTRPA1) activated by increasing concentrations of allyl isothiocyanate (AITC). hTRPA1 could be repetitively stimulated using low concentrations of AITC but was desensitized by high concentrations of AITC (>10 μM).