UHPLC Retention Time Prediction Using ACD/ChromGenius Increases Efficiency in Investigative Monitoring of Emerging Contaminants

In this application note, the retention time prediction capabilities of ACD/ChromGenius are outlined, and a suggestion of how these can be incorporated into a typical investigative water monitoring workflow is also included. Specifically, ultra-high performance liquid chromatography (UHPLC) retention time estimates for over 100 pharmaceuticals are evaluated by comparing predictions to measured values from a curated online database.