Using GPC/SEC for Excipient Characterization

This article looks at how gel permeation/size‑exclusion chromatography (GPC/SEC) can be applied to measure characteristics such as molecular weight (MW), MW distribution and structure, and degree of branching. Case study data for the measurement of poly‑lactic acid (PLA) and poly‑lactic glycolic acid (PLGA) highlights the detailed information that can be accessed.