Validation of a New Rapid Free-Light-Chain Test (Seralite®) for the Diagnosis and Monitoring of Plasma Cell Dyscrasias

Monoclonal kappa (κ) or lambda (λ) immunoglobulin free light chains (FLC), produced from malignant plasma cell clones, are important biomarkers for the diagnosis and monitoring of plasma cell dyscrasias, including multiple myeloma. This poster shows that the rapid assay, Seralite®, has superior diagnostic sensitivity compared to immunofixation electrophoresis, and can provide clinically valid quantitation of κ and λ FLC in serum and urine within 10 minutes.