Vanoxerine, a New Drug for Terminating Atrial Fibrillation

Vanoxerine is a dopamine transporter antagonist that was developed for treatment of Parkinson’s disease and depression, but had no effect on these diseases. This application note demonstrates that vanoxerine is highly effective in terminating atrial fibrillation (AF) or atrial flutter (AFL) in dogs with sterile pericarditis (SP) and has the potential to become a valuable antiarrhythmic agent.