Virus Purification Strategies

Viral particles form an ever-increasingly important class of biologics, with applications in vaccine development, disease prevention and as delivery mechanisms for gene therapy and the treatment of diseases such as cancer.

In addition to their important biotherapeutic potential, biological study and characterization of virus infectivity, reproduction and host immune system evasion are of continued importance. Ensuring that virus production and purification are of the highest quality for effective recovery of particles is therefore vital for both research and therapy.

In this application eBook, we look at methodologies, chromatography systems and ion exchange resins for optimized virus process purification to achieve increased productivity and improved economics, covering:

• Challenges in virus production
• Choosing the right chromatography media
• Purification method development