Xanthine derivatives on a C12 column

Evosphere^® columns incorporate optimised bonding and packing practices with a fully porous monodisperse particle. This provides the analyst with the ability to speed up analysis, increase efficiency and improve resolution over ‘traditional’ 3 µm and 5 µm particles even on normal 400 bar HPLC systems. In this application note, Mac-Mod introduces xanthine derivatives theobromine, theophylline and caffeine on an Evosphere C12 150 x 4.6 5 µm column with a flow of 1.0 mL/min.