Scientific PostersComparison of Chemical Inhibitors versus Genetic Knock-Out Cell Models for Identification of PGP and BCRP Substrates in Caco-2 Cell Lines
Scientific PostersUtilizing Two High Content Screening Assays; HCS-Phospholipidosis and HCS-Lysosomal Trapping and In Silico Modeling Approaches in Predicting <i>In Vivo</i> Phospholipidosis
Scientific PostersDevelopment of an <i>in vitro</i> Multiwell Multielectrode Array (MEA) Neurotoxicity Assay with Human iPS Derived Neurons
Scientific PostersEvaluation of Species and Tissue-Dependent Differences Observed in Carboxylesterase Metabolism: Application to Pro-Drug Studies
Scientific PostersEvaluation of High Content Mechanism Screening as a Prediction Tool for Organ Toxicity
Scientific PostersScreening for EADs and Pro-Arrhythmic Potential with Human iPS Derived Cardiomyocytes using a Multiwell Microelectrode Array (MEA)
Scientific PostersUse of Physiologically-Based Pharmacokinetic Modeling (PBPK) in Conjunction with CellCiphr HCS to Predict Compound Safety Thresholds and Improve Lead Optimization
Scientific PostersDevelopment of an <i>in vitro</i> Multiwell Cardiovascular Multielectrode Array (MEA) Toxicity Assay with Human IPS Cell Derived Cardiomyocytes
Scientific PostersPotential Cholestatic Drugs Assessed by Membrane Transport Vesicle Assays as Well as Bile Canaliculi Inhibition in Primary Hepatocytes
Scientific PostersMethods for Improving <i>in vitro</i> Prediction of Intrinsic Clearance Utilizing 3d Cell Culture Models
Scientific PostersDevelopment of an LC/MS/MS Screening Method to Evaluate the Impact of Drugs on Cortisol Biosynthesis <i>in Vitro</i>
Scientific PostersUtility Of Different Test Systems For Determining Carboxylesterase Substrate Specificity And Inhibition Potential
Scientific PostersBSEP and MRP2 Transport Vesicle Screening Assays for the Prediction of Potential Cholestatic and Drug-Induced Liver Injury
Scientific PostersChallenges in the Development of In Vitro Screens for Assessing Non-CYP Mediated Metabolism
Scientific PostersAn In vitro Screening Method to Evaluate the Drug-Drug Interaction Due to Inhibition of Sulfotransferase Enzymes (SULTS)
Scientific PosterseCiphrNeuro: A High Throughput Assay to Detect Neurotoxic Compounds in Early Drug Discovery
Scientific PostersComparison of in vitro Cellular Approaches to Investigate Metabolism-mediated Toxicity using High Content Screening