Search results for "molecular microbiology"

On-Bead Antibody-Small Molecule Conjugation and pH Sensor Fluorescent Dye for Screening of Internalizing Antibodies for ADC Applications

The basic Nucleofector® II Device is a single cuvette based system that has been used in research labs since 2001. It allows efficient transfection of hard-to-transfect cell lines and primary cells with different substrates, e.g. DNA vectors or siRNA oligonucleotides, in low throughput format. What benefits are important for your work? Efficient transfection in single cuvette format? Up to 90% efficiency with plasmid DNA…

A Sensitive solution for HPLC, fast-LC and CE systems High Sensitivity: 10 times to 100 times greater than conventional fluorescence and up to 100,000 times more sensitive than UV detection. Versatility: 14 interchangelable different lasers availables for any application Modularity : Adaptable to CE and HPLC systems including Fast-LC, Capillary LC and nanoLC.Selectivity: Low noise and interference molecules will be detected.…

The Bio-Plex Pro Human Cytokine Screening Panel enables you to interrogate 17 cytokine and chemokine cell signaling molecules in complex extracellular events and signaling pathways involved in heart disease, Alzheimer's disease, autoimmunity and allergy, infectious diseases, inflammation, cancer, and neurodegeneration. This high-performance, broad screening panel consists of a biologically-relevant collection of adaptive immun…

The next generation NanoLC system from Eksigent promises to deliver high resolution separations, combined with excellent reproducibility, resulting in improved identification of low abundance peptides, proteins, and small molecules with nanoLC-MS. The higher pressure capability of the NanoLC-Ultra® platform allows the use of longer columns and/or columns packed with smaller particles for higher resolution separations of comple…

Use the new Thermo Scientific™ MAbPac™ RP columns for high-performance reversed-phase (RP) HPLC and LC/MS characterization of monoclonal antibodies (mAbs), fragments, variants, antibody drug conjugates (ADCs), PEGylated proteins, and bispecific proteins. These columns have excellent resolution, long column lifetime, and low carry-over. The surface chemistry, particle size, and pore size, have been optimized to for high resolut…

Automates sample preparation in preparation for amplification and detection Automates the sample preparation steps of real-time polymerase chain reaction (PCR) testing for analysis on the COBAS® TaqMan® Analyzers. This instrument operates with robotic precision to dramatically reduce hands-on time and enhance user productivity. It can be used for diagnostic applications and for screening pools of blood donations in clinical la…

Ion AmpliSeq HD technology is a new amplicon-based library preparation technology for Ion Torrent next-generation sequencing (NGS) that gives you the power to design your own panels and find variants with a low limit of detection—down to 0.1% for cell-free DNA samples. This revolutionary technology enables researchers to routinely get answers when ultrahigh sensitivity is required, such as when detecting low-frequency alleles…

We make and supply spectrometers designed to familiarise students with the principles of fluorescence lifetime spectroscopy and in particular time correlated single photon counting (TCSPC). By monitoring the fluorescence lifetimes of emitting dyes, important information can be obtained on the molecular interactions and the micro-environment of these dyes. Proximity of quenchers, the presence of oxygen, pH level, temperature an…

The Mark12 Unstained Standard allows the closest estimation of molecular weight of your sample protein over a wide molecular weight range.

Molecular Biology Reagents

Molecular Biology Reagent  

Molecular Biology Reagent  

Application Duolink® proximity ligation assay(PLA®) allows for endogenous detection of protein interactions, post translational modifications, and protein expression levels at the single molecule level in fixed cells and tissue samples. Follow the Duolink® In Situ Fluorescence Protocol to use this product. A set of short instructionsis also available. Visit our Duolink® PLA Resource Center for information on how to ru…

High-resolution separations of peptides and tRNA molecules: LiChrospher® WP 300 RP-18 is a highly selective and reliable HPLC column for the separation of peptides and low molecular weight proteins. LiChrospher® WP 300 RP-18 enables the tailing-free separation of basic compounds and is excellently suited for the separation of tRNA molecules. High recovery rates are achieved, especially in the case of highly hydrophobic pepti…

The new PET Inline Module unfolds the power of functional molecular imaging with multiparametric molecular imaging beyond PET quantification based on excellent morphological contrast.

Reversed Phase Method Development that's Simple, Fast, Effective, and Universal!•Boasts the widest range of reversed phase selectivity in the industry.•Simplifies column selection down to 4 unique stationary phases.•Employs orthogonal selectivity to speed up effective method development.•Maximizes efficacy of your column screening systems.•Fits any HPLC or UHPLC instrumentation. Restek Ultra Selective Liquid Chromatography™ (…

Trypsin is a serine protease that specifically cleaves at the carboxylic side of lysine and arginine residues.   The stringent specificity of trypsin is essential for protein identification. Native trypsin is subject to autolysis, generating pseudotrypsin, which exhibits a broadened specificity including a chymotrypsin-like activity. Such autolysis products, present in a trypsin preparation, would result in addition…