Editorial ArticleLife Sciences
Overcome common hurdles in scaling up mRNA-based therapeutics
Explore ways to resolve three of the key challenges in the field of mRNA-based therapies
RNA interference (RNAi) uses siRNA or miRNA for transcriptional silencing, gene knockdown and regulation of gene expression. RNAi requires chemical synthesis, introduction of DNA vectors into cells, an assay of RNAi effects and RNAi quantification or analysis. Consider target sequence selection, reagent preparation, controls, high specificity and effectiveness and low non-specific gene knockdown.
Explore ways to resolve three of the key challenges in the field of mRNA-based therapies