Incorporating the Extracellular Matrix: New Challenges and Opportunities in Cancer Research

At least 80% of cancers are carcinomas, or tumours of the epithelia. Traditionally, cell transformation to a cancerous stage was evaluated by anchorage dependent growth, an assay more suited for fibroblasts. More recently, the role of the extracellular matrix (ECM), already established in normal epithelial biology, has come to the fore in the study of carcinomas. Watch the video to find out more about ECM proteins, substrates, 3D cell culture products and services most relevant to cancer research and drug screening.