Streamlining lipid nanoparticle characterization with a hands-free approach

The RiboGreen assay is a common method for assessing lipid nanoparticle (LNP) encapsulation efficiency, but it is labor-intensive, error-prone, and lacks insight into therapeutic parameters like mRNA integrity.

Mojca Bavčar, Associate Scientist at Sartorius BIA Separations, introduces the PATfix LNP Switcher^®, a 2D chromatography system that enables accurate size estimation and encapsulation efficiency analysis. Discover how this instrument can minimize sample preparation by offering a hands-free approach while delivering valuable therapeutic insights, all within a single assay.