Discovering novel immunological clues in small fiber neuropathy with innovative techniques

Small fiber neuropathy (SFN) is under-diagnosed and under-recognised, due to lack of diagnostic tools in other centers. However, we now know that SFN is much more prevalent than once thought and is much more common than other inflammatory neurological disorders. Therefore, it is imperative to further research this new entity.

Over 50% of patients suffer from idiopathic SFN, i.e. the cause is still unknown. Despite multiple suggestions of association between autoimmunity with SFN, few autoantibodies or immune compounds have been described. Dr. Chan’s primary research focus is to identify the etiology and pathophysiology of SFN, with a focus on immunological mechanisms.

In this webinar, Dr. Chan will review the current literature on autoimmunity in SFN, and her journey into discovering novel autoantibodies in idiopathic SFN with the innovative Sengenics KREX platform, the results of which were just published in the highly impactful Annals of Neurology. By understanding more about the pathophysiology, Dr. Chan hopes to develop precision treatments for her patients with debilitating SFN symptoms.

Key learning objectives

  • Understand the link between SFN and autoimmunity
  • Understand the role of autoantibodies in idiopathic SFN
  • Use of Sengenics KREX platform in autoantibody discovery
  • Insight into the etiology and pathophysiology of SFN

Who should attend

  • Researchers who study SFN
  • Researchers who are interested in autoimmune pathology and diseases
  • Researchers with interest in biomarker discovery
  • Academics, pharmaceutical and clinical researchers interested in precision medicine

Certificate of attendance

All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.

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