Fiber chromatographic clarification platform revolutionizes bioprocess strategy

Working in cell culture can be challenging, particularly when working with larger density cultures. In research, collecting higher concentrations of titers for biopharmaceutical manufacturing is a crucial technique that aims to obtain optimal purity.

New fiber chromatographic clarification technology from Solventum is designed to filter impurities by charge, rather than the conventional method of particle size. This technique removes a higher depth of impurities compared to traditional filters resulting in a higher yield of positively charged molecules of interest.

In this presentation, now available on demand following the recent SelectScience^® Biopharma Summit 2024, Dr. Masa Nakamura, a Bioprocess Science Senior Specialist, Solventum, articulates how this technology has elevated his drug discovery and highlights how focusing on charge based chromatographic clarification could be the way forward.