Quality matters: Tackling high molecular weight DNA contamination in cell-free DNA for optimal liquid biopsy NGS
Tuesday, June 24, 2025 at 16:00 BST / 17:00 CEST / 11:00 EDT / 08:00 PDT
Cell-free DNA (cfDNA) has become an essential tool in clinical research and serves as valuable biomarker in liquid biopsy applications. However, cfDNA presents a challenge for Next-Generation Sequencing (NGS) workflows due to its low yield, complex fragmentation pattern and potential presence of contaminating high molecular weight (HMW) DNA.
In this webinar, our expert speaker will discuss reliable pre-analytical quality control using the Agilent Cell-free DNA ScreenTape assay and the TapeStation systems, emphasizing their relevance to NGS-based liquid biopsy applications.
Key learning objectives
- Understand the challenges associated with cfDNA extraction and HMW DNA contamination.
- Learn about the impact of HMW DNA on cfDNA quality and NGS results.
- Explore how to ensure pre-analytical quality control of cfDNA samples.
- Discover the unique benefits of the Agilent Cell-free DNA ScreenTape assay for obtaining the full picture of your cfDNA quality.
Who should attend?
NGS and genomics researchers, molecular biologists, researchers in cancer diagnostics and liquid biopsy, and sequencing lab managers and technicians
Certificate of attendance
If you attend the live webinar, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
If you view the on-demand webinar, you can request a certificate of attendance by emailing editor@selectscience.net.
For Research Use Only. Not for use in diagnostic procedures. PR7001-4363
Speakers
Annika Dorn, PhD, is a product manager within the automated electrophoresis marketing team at Agilent Technologies and is based in Waldbronn, Germany. Since joining Agilent in 2021, she has been responsible for the Agilent ScreenTape product portfolio. Prior to her tenure at Agilent, she completed a 5-year postdoctoral fellowship at the Karlsruhe Institute of Technology, Germany, where she focused on cutting-edge research in plant molecular biology and genome engineering.
Moderator
