Quantitative characterization of asthma inhalation blends using correlative, AI powered X-ray microscopy

Discover the interdependent relationship between the structure, properties, and performance of drugs in pharmaceutical material science.

In this webinar, Dr. Ben Tordoff, Head of Materials Science Business Sector at ZEISS Research Microscopy Solutions, Parmesh Gajar, principal scientist at the University of Manchester and Darragh Murnane, Professor of Pharmaceutics at the University of Hertfordshire will discuss the importance of the microstructure for producing respirable particles for effective therapeutic benefits of a typical dry powder inhaler (DPI) formulation.

Additionally, they will describe how X-ray microscopy (XRM) can be combined with molecular modeling to calculate inter-particulate forces that underpin powder cohesion. They will also explain how the LabDCT technique can be utilized to gather 3D crystallographic information on crystalline bulk powders of lactose particles.

Finally, they will illustrate how artificial intelligence (AI) image analysis is used to visualize the powder microstructure and simulate the drug release performance.

Key learning objectives

  • Learn how to evaluate heterogeneous microstructures
  • Discover how to combine crystallographic information and micro-CT imaging
  • Understand why drug delivery is dependent on the microstructure and how it can be simulated

Who should attend?

  • Materials researchers from academia and industry, X-ray microscopy users, drug designers, pharmaceuticals material researchers, PhD students, principal investigators, and lab managers

Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.

Speakers

Ben Tordoff
Ben Tordoff
ZEISS Research Microscopy Solutions
Darragh Murnane
Darragh Murnane
University of Hertfordshire
Lawrence Howes
Lawrence Howes
Editorial Assistant, SelectScience
Parmesh Gajar
Parmesh Gajar
Principal Scientist & Research Associate (School of Materials Science), University of Manchester

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