Spatial signature panel optimization and reproducibility to enable tumor immune profiling

Dr. Cara Haymaker will discuss her research and the work within the TMP-IL platform focused on the development and reproducibility of an automated nine-colour mIF panel to visualize and characterize the TME. The findings demonstrated the power of multiplex imaging in exploring cellular phenotype proliferation in the TME and their geographic distribution and spatial proximity of cell phenotypes related to malignant cells. This research has implications for the potential capability of the data obtained through this methodology for immune profiling FFPE tumor tissues in translational studies.

Key learning objectives

• Understand how multispectral imaging can be used to profile many different cell types in the tumor microenvironment.
• Learn about the methods for the optimization and reproducibility of a 9-color multiplex immunofluorescence panel.

Who should attend?

• Translational and Clinical researchers
• Scientists in biopharmaceuticals
• CROs

Certificate of attendance

All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.