Validating an expanded list of PFAS compounds from C4-C18 chain length

Exposure to manmade perfluoroalkyl and polyfluoroalkyl substances (PFAS) is of increasing concern due to their potential toxic effects and links to ecological damage and human health. These substances can be found in drinking, surface, waste and ground waters, but are also prevalent in food, household products, and even living organisms including fish and humans.

Recently, the state of California has expanded the required list of PFAS for analysis in wastewaters up to 42 PFAS compounds from C4 to C18 including carboxylic and sulfonic acids, sulfonamide derivatives, telomers, and ethers.

There are several methods for PFAS analysis, including ISO and EPA methods that are validated for a specific list of PFAS compounds using SDVB or WAX SPE for extraction and preconcentration prior to analysis by LC-MS/MS. However, the US Department of Defense (DOD) quality assurance manual suggests using a two-step SPE approach using WAX followed by a graphitized carbon black (GCB) cleanup.

In this webinar, David Schiessel, Babcock Labs, and Richard Jack, Phenomenex, will demonstrate the use of a dual, stacked WAX/GCB SPE method that uses a single step for C4-C18 PFAS compounds from waste-, surface- and groundwater extracts followed by LC-MS/MS.

Key learning objectives

• Find out more about the mission and work being performed by Babcock Laboratories for PFAS testing in water samples
• Method compliance using DoD QSM 5.3 standard for the expanded list of 42 PFAS compounds from the CA Resources Board from C4-C18
• Achieve robust and sensitive extraction and analysis using Strata-PFAS SPE followed by LC-MS/MS

Who should attend?

• Academic laboratories performing analytical chemistry research on emerging and existing environmental contaminants
• Country and state laboratories responsible for PFAS analysis
• Public water utilities or contract testing laboratories performing targeted PFAS testing

Certificate of attendance

All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.