Why is ion mobility mass spectrometry becoming the must have tool in life sciences research?

The coupling of ion mobility with mass spectrometry has developed into a powerful and widely used separation technique with applications in many research areas across the biological sciences. In this webinar, Professor Ian Wilson and Professor Kostas Thalassinos, from University College London, highlight the benefits of IM-MS for two different application areas.

Probing the structure and dynamics of proteins by means of a cyclic ion mobility spectrometry traveling wave device

Prof. Thalassinos will demonstrate how traveling wave cyclic ion mobility enables the detailed study of proteins and protein complexes without significantly affecting their structure and how tandem ion mobility experiments allow the study of protein behavior not observable using other techniques.

Ion mobility MS enabled metabolic and lipid profiling

Prof. Wilson describes how the inclusion of ion mobility within rapid metabolic and lipid phenotyping workflows increases throughput and provides cleaner data to aid database searching, and how calculated and measured collision cross-section values can be compared to increases confidence in the identification of potential biomarkers.

Key learning objectives:

• Discover how novel cyclic ion mobility revolutionizes protein confirmation studies
• Learn new bioinformatic approaches to processing multidimensional ion mobility data
• Explore how adding ion mobility increases peak capacity and improves high-throughput methodologies for large-scale phenotyping studies
• Understand the role of collision cross-section measurements in increasing confidence in metabolite identification

Who should attend?

• Everybody interested in the latest advances in ion mobility mass spectrometry
• Core laboratory scientists
• Biomedical researchers

Certificate of attendance

All webinar participants can request a certificate of attendance, and a learning outcomes summary document for continuing education purposes.

This webinar is part of the SelectScience Advances in Mass Spectrometry Webinar Series>>