Zooming in on B cells and viruses: The power of flow virometry and cell sorting

Virus-like particles (VLPs) are nanostructures that possess diverse applications in therapeutics, immunization, and diagnostics. These particles consist of one or more different molecules, have the ability to self-assemble, and are virus particle mimics in that they share the same form and size. However, they lack the proper genetic material to be infectious. Recently, VLPs have garnered increased attention in relation to SARS-CoV-2 vaccination. Due to their ability to elicit an immune response, VLPs have become an attractive alternative to conventional vaccination methods, for which contaminants from host cell production are a major issue. In this webinar, join our expert speakers as they discuss how flow virometry isolates and characterizes VLPs more efficiently by selectively capturing VLPs of interest. In addition, they will explore how cell sorting techniques have been used to deepen understanding of how humoral immunity is developed to viral antigens, describing how both follicular helper T cells and follicular regulatory T cells have an effect on germinal center reactions.

Key learning objectives

• Understand what VLPS are and how are they beneficial to research
• Learn more about the immunologic response to SARS-CoV-2 and associated pathways
• Explore sorting as a research tool for vaccine research

Who should attend?

Laboratory managers, Principal investigators, and Flow cytometry core facility employees

Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.