Product & ReviewsAntibodies
14-3-3 (Ser58) Antibody
Product Details
- Cat. No.
- 252518
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
14-3-3 protein beta/alpha (14-3-3) is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. p1433-58 binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. p1433-58 binding generally results in the modulation of the activity of the binding partner. p1433-58 is a negative regulator of osteogenesis. Recent work has demonstrated that the dimeric status of the 14-3-3 protein is regulated by site-specific serine phosphorylation.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Chicken, Dog (Canine), Human, Mouse, Sheep (Ovine), Xenopus, Zebrafish
- Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser58 of rat 14-3-3.
- Isotype: Rabbit Ig
- Modifications: Phosphospecific Antibody
- Gene: P35213
Handling
- Quantity: 0.1 ml
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)