Product & ReviewsAntibodies

4E-BP1 (Phospho-Thr45) antibody

Product Details

Cat. No.
orb106242
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Biorbyt

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Description

Rabbit polyclonal to 4E-BP1 (Phospho-Thr45). 4E-BP1 binds to eIF4E, preventing its assembly into the EIF4F complex and inhibiting cap-dependent translation. Phosphorylation of 4E-BP1 disrupts this binding, activating cap-dependent translation.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human, Mammalian, Mouse
  • Isotype: IgG

Handling

  • Quantity: 50 µl, 100 µl, 20 µl
  • Storage: Store at -20°C.Stable for 12 months from date of receipt.
  • Buffer: Phosphate buffer saline, pH. 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Applications

  • Immunohistochemistry (Paraffin-Embedded Sections) (IHC (P))
  • Western Blotting (WB)
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