Product & ReviewsAntibodies
ABCE1 Antibody
Product Details
- Cat. No.
- 251984
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
ATP-binding cassette sub-family E member 1 (ABCE1) antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. ABCE1 plays a central role in the regulation of mRNA turnover. ABCE1 antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway, an acts as a chaperone for post-translational events during HIV-1 capsid assembly.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ABCE1.
- Isotype: Rabbit Ig
- Gene: P61221
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)