Acetylated Lysine Antibody
Product Details
- Cat. No.
- 251118
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
DNA transcription cannot take place unless DNA is unwound from the nucleosomes. The cell unwinds DNA by acetylation of lysine residues of histones. Research has shown that acetylation of non-histone proteins (e.g. transcription factors) and histones are involved in transcription. Histone acetyltransferases (HAT) acetylate the conserved amino-terminal domains of the four core histones (H2A, H2B, H3 and H4) on lysine residues, whereas histone deacetylases (HDAC) remove them. This pan-specific antibody recognizes proteins with acetyllysine residues. This antibody has been utilized for proteomic studies of protein acetylation, immunoaffinity chromatography separation and isolation of acetylated proteins and peptides from protease-digested whole cells.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: Acetylated KLH-conjugates
- Conjugate: FITC-conjugated Antibody
- Isotype: Rabbit Ig
- Modifications: Modification Specific Antibody
Handling
- Quantity: 0.1 mg
- Storage: Store at 4°C. Minimize freeze-thaw cycles. Product is guaranteed 6 months from the date of shipment.
Applications
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)