Adiponectin Antibody
Product Details
- Cat. No.
- 252006
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Adiponectin is an adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Adiponectin stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Defects in adiponectin are the cause of adiponectin deficiency (ADPND). ADPND results in very low concentrations of plasma adiponectin. Genetic variations in adiponectin are associated with non-insulin-dependent diabetes mellitus (NIDDM), also known as diabetes mellitus type 2. NIDDM is characterized by an autosomal dominant mode of inheritance, onset during adulthood and insulin resistance.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human adiponectin.
- Isotype: Rabbit Ig
- Gene: Q15848
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)