ADRB2 Antibody
Product Details
- Cat. No.
- 251604
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
The beta-2 adrenergic receptor is a G-protein coupled adrenergic receptor with 30-fold higher affinity for epinephrine than norepinephrine. Agonist binding to the beta-2 adrenergic receptor initiates signal transduction pathways via activation of adenylyl cyclases. There are numerous physiological effects of beta-2 adrenergic receptor activation, including smooth muscle relaxation, blood vessel dilation, increased heart rate, and insulin secretion. The Gly-16 allele is overrepresented in individuals affected by nocturnal asthma as compared to controls, and appears to be an important genetic factor in the expression of this asthmatic phenotype.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Chimpanzee, Dog (Canine), Guinea Pig, Human, Monkey, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ADRB2.
- Isotype: Rabbit Ig
- Gene: P07550
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)