Product & ReviewsAntibodies
AID rat antibody (mAb) (Clone 328.8b), sample
Product Details
- Cat. No.
- 39886
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rat
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Description
AID (Activation-induced cytidine deaminase) is a member of the cytidine and deoxycytidylate deaminase family. It acts act as a single-strand DNA deaminase involved in somatic hypermutation, gene conversion and class-switch recombination in developing B-cells and is necessary for efficient antibody responses. It has also been implicated in active DNA demethylation, as deamination of methylcytosine yields thymine, which is read as a mismatch and is replaced by DNA damage repair enzymes.
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Human, Mouse
- Clone: 328.8b
- Isotype: IgG2a
Handling
- Quantity: 10 ug
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Western Blotting (WB)