Product & ReviewsAntibodies
AIF Antibody
Product Details
- Cat. No.
- 250463
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Mouse
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Description
Apoptosis-inducing factor (AIF) is a mitochondrial protein that translocates to the nucleus upon induction of apoptosis. It has been demonstrated that AIF causes DNA fragmentation and chromatin condensation, and induces the release of cytochrome c and caspase-9 from mitochondria. Release of AIF from mitochondria was shown to be prevented by over-expression of Bcl-2, a protein involved in mitochondrial permeability.
Biological Information
- Clonality: Polyclonal
- Host: Mouse
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human AIF protein.
- Isotype: Mouse Ig
- Gene: O95831
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blotting (WB)