Product & ReviewsAntibodies

AIF Antibody

Product Details

Cat. No.
250463
Type
Primary Antibody
Clonality
Polyclonal
Host
Mouse
Abbiotec

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Description

Apoptosis-inducing factor (AIF) is a mitochondrial protein that translocates to the nucleus upon induction of apoptosis. It has been demonstrated that AIF causes DNA fragmentation and chromatin condensation, and induces the release of cytochrome c and caspase-9 from mitochondria. Release of AIF from mitochondria was shown to be prevented by over-expression of Bcl-2, a protein involved in mitochondrial permeability.

Biological Information

  • Clonality: Polyclonal
  • Host: Mouse
  • Reactivity: Human, Mouse, Rat
  • Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human AIF protein.
  • Isotype: Mouse Ig
  • Gene: O95831

Handling

  • Quantity: 0.1 mg
  • Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Applications

  • ELISA (ELISA)
  • Immunohistochemistry (IHC)
  • Immunoprecipitation (IP)
  • Western Blotting (WB)
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