AKR1A1 Antibody
Product Details
- Cat. No.
- 252018
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Alcohol dehydrogenase [NADP+] (AKR1A1) catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. AKR1A1 catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. AKR1A1 has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. AKR1A1 plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human AKR1A1.
- Isotype: Rabbit Ig
- Gene: P14550
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)