Product & ReviewsAntibodies

Alpha-1 Antitrypsin Antibody

Product Details

Cat. No.
250475
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Abbiotec

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Description

AAT (Alpha-1-antitrypsin) is an inhibitor of serine proteases. Although AAT's primary target is elastase, the enzyme has also a moderate affinity for plasmin and thrombin. AAT inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. AAT deficiency is related to emphysema and liver disease.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Bovine, Dog (Canine), Human, Mouse, Pig (Swine), Rabbit (Lapine), Rat, Sheep (Ovine)
  • Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human AAT.
  • Isotype: Rabbit Ig
  • Gene: P01009

Handling

  • Quantity: 0.1 mg
  • Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Applications

  • ELISA (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blotting (WB)
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