Product & ReviewsAntibodies
Alpha-1 Antitrypsin Antibody
Product Details
- Cat. No.
- 254500
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
AAT (Alpha-1-antitrypsin) is an inhibitor of serine proteases. Although AAT's primary target is elastase, the enzyme has also a moderate affinity for plasmin and thrombin. AAT inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. AAT deficiency is related to emphysema and liver disease.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Dog (Canine), Human, Mouse, Pig (Swine), Rabbit (Lapine), Rat, Sheep (Ovine)
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human AAT.
- Conjugate: Biotin-conjugated Antibody
- Isotype: Rabbit Ig
- Gene: P01009
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed 6 months from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)