Product & ReviewsAntibodies
Alpha-4 Integrin Antibody
Product Details
- Cat. No.
- 251867
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Integrin alpha-4 (CD49d) is a receptor for fibronectin. Integrin alpha-4 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-4 is also a receptor for VCAM1, recognizing the sequence Q-I-D-S in VCAM1, and a receptor for MADCAM1, recognizing the sequence L-D-T in MADCAM1. On activated endothelial cells, integrin alpha-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines, and also participates in cytolytic T-cell interactions with target cells.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human integrin alpha-4.
- Isotype: Rabbit Ig
- Gene: P13612
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunocytochemistry (ICC)
- Immunohistochemistry (IHC)
- Western Blotting (WB)