Product & ReviewsAntibodies
Alpha-5 Integrin Antibody
Product Details
- Cat. No.
- 250731
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
The integrin alpha-5 antibody recognizes the 115-kDa transmembrane glycoprotein integrin alpha-5 subunit which is the common alpha-5 chain of the very late antigen (VLA) forming a non-covalent heterodimeric complex with the integrin beta-1 subunit, a receptor for fibrinogen and extracellular matrix proteins such as fibronectin. Alpha-5/beta-1 integrin is an important adhesion molecule involved in cell-cell and cell-extracellular matrix interactions by recognizing the RGD canonical sequence in ligands. In addition to adhesion, integrins are known to participate in cell-surface mediated signaling.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Human, Mouse, Pig (Swine), Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human integrin alpha-5.
- Isotype: Rabbit Ig
- Gene: P08648
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)