Product & ReviewsAntibodies
Alpha-actinin-4 Antibody
Product Details
- Cat. No.
- 252035
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Alpha-actinin-4 is a cross-linking protein which is thought to anchor actin to a variety of intracellular structures. Alpha-actinin-4 is involved in vesicular trafficking via its association with the CART complex. Defects in alpha-actinin-4 are the cause of focal segmental glomerulosclerosis type 1 (FSGS1), a renal pathology defined by the presence of segmental sclerosis in glomeruli and resulting in proteinuria, reduced glomerular filtration rate and edema.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human alpha-actinin-4.
- Isotype: Rabbit Ig
- Gene: O43707
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)