Product & ReviewsAntibodies
AMPK alpha-1 Antibody
Product Details
- Cat. No.
- 251485
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK alpha-1) is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. AMPK alpha-1 also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. AMPK alpha-1 acts as a metabolic stress-sensing protein kinase that switches off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human protein C-AMPK alpha-1.
- Isotype: Rabbit Ig
- Gene: Q13131
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)