Product & ReviewsAntibodies
Androgen Receptor (2H8) Antibody
Product Details
- Cat. No.
- 252967
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
AR (Androgen receptor) is a member of the steroid superfamily of ligand-dependent transcription factors. They regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. AR consists of an amino terminal modulating domain, a central DNA-binding domain, a hinge region and a carboxyl terminal ligand binding domain. Defects in AR are the cause of androgen insensibility syndrome (genital disorders), X-linked spinal and bulbar muscular atrophy (Kennedy disease), metastatic prostate cancer and infertility male syndrome.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Purified recombinant fragment of human AR expressed in E. coli.
- Clone: 2H8
- Isotype: Mouse IgG1
- Gene: P10275
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Immunohistochemistry (IHC)
- Western Blotting (WB)