Product & ReviewsAntibodies
ANG2 Antibody
Product Details
- Cat. No.
- 252056
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Angiopoietin-2 (ANG2) induces tyrosine phosphorylation of TIE2. ANG2 binds to the TIE2 receptor and counteracts blood vessel maturation/stability mediated by angiopoietin-1. ANG2 function is context-dependent: In the absence of angiogenic inducers, such as VEGF, ANG2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, ANG2 facilitates endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ANG2.
- Isotype: Rabbit Ig
- Gene: O15123
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)