Product & ReviewsAntibodies
Ankyrin-1 Antibody
Product Details
- Cat. No.
- 252063
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Ankyrin-1 attaches (ANK1) integral membrane proteins to cytoskeletal elements. Erythrocyte ankyrins link spectrin (beta chain) to the cytoplasmic domain of the erythrocytes anion exchange protein. Defects in ANK1 are a cause of spherocytosis type 1 (SPH1), also called hereditary spherocytosis type 1 (HS1). Spherocytosis is a hematologic disorder leading to chronic hemolytic anemia and characterized by numerous abnormally shaped erythrocytes which are generally spheroidal. Inheritance can be autosomal dominant or recessive.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ankyrin-1.
- Isotype: Rabbit Ig
- Gene: P16157
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)