Product & ReviewsAntibodies

anti-AAV VP1/VP2/VP3 mouse monoclonal, B1, liquid, purified

Product Details

Cat. No.
690058
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
PROGEN

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Description

<p>The B1 antibody reacts with free VP1, VP2 and VP3 of adeno-associated virus (AAV) and at a reduced degree with assembled viral particles. VP1 and VP2 are highly enriched in the nucleus, while non-assembled VP3 is evenly distributed in the nucleus and the cytoplasm. Epitope mapping experiments (Wobus et al., 2000) identified aa726 to aa733 (C-terminus; common to all 3 VP proteins) as the specific binding region. The antibody is also useful for characterization of different stages of infection.</p><p>Wobus, C. E. et al. Monoclonal antibodies against the adeno-associated virus type 2 (AAV-2) capsid: epitope mapping and identification of capsid domains involved in AAV-2-cell interaction and neutralization of AAV-2 infection. J. Virol. 74, 9281-93 (2000).</p> <p>Limited Use Label License: Research Use Only</strong><br>Product is exclusively licensed to PROGEN Biotechnik GmbH. The use of these products for the development, manufacturing and sale of secondary products/derivatives which are based on the purchased products and/or which include the purchased product require a royalty based sub-license agreement.</p>

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse

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