For characterization of different stages of infection and very useful for the analysis of the AAV assembly process. ADK8 specifically reacts with AAV1, AAV3, AAV7, AAV8, AAVrh10, AAVrh74 and Anc80, empty and full capsids. Recognizes a conformational epitope of assembled capsids. Predicted binding site: residues 586-LQQQNT-591 (Gurda et al. 2012). The antibody cannot be used for immunoblotting using denaturing conditions. The antibody is also useful for neutralizing experiments. Gurda, B. L
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Adeno-Associated Virus
- Antigen: AAV8 capsids
- Clone: ADK8
- Conjugate: unconjugated
- Isotype: IgG2a kappa
- Quantity: 50 µg
- Storage: short term at 2-8°C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
- Specificity: 5
- Dot Blot (DB)
- ELISA (ELISA)
- Immunocytochemistry (ICC)
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Neutralization (Neut)