Anti-ALPL polyclonal antibody [HRP]
Product Details
- Cat. No.
- CPBT-66503SH
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Sheep
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Description
Sheep Anti-Human ALPL polyclonal antibody for ELISA. Sheep anti Human alkaline phosphatase (Bap) antibody recognizes human bone alkaline phosphatase (BAP), a membrane-bound hydrolase enzyme expressed by osteoblast cells. Alkaline phosphatase (AP) is a ubiquitously expressed enzyme which removes phosphate groups from target molecules, including DNA, RNA and alkaloids, under alkaline conditions, and is present at higher concentrations in the placenta (placental AP), intestines (intestinal AP) and liver/bone/kidney (tissue non-specific AP). Although the exact biochemical function of BAP is uncertain, measurement of the serum levels of BAP can be used as a biochemical indicator of bone turnover. Conditions which present with a decrease in the level of BAP (hypophosphatasemia) include the inherited bone-deforming disorder hypophosphatasia and osteoporosis, whilst an increase in BAP (hyperphosphatasemia) is associated with Paget's disease, bone fractures and osteosarcomas. Applications：ELISA
Biological Information
- Clonality: Polyclonal
- Host: Sheep
- Reactivity: Human
- Conjugate: HRP
- Isotype: Polyclonal IgG
- Gene: 249
Handling
- Quantity: 1 ml
- Storage: in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)