Arginase-1, encoded by the ARG1 gene, is a cytosolic metalloenzyme expressed predominantly inhepatocytes. Arginase-1 plays a key role in the urea cycle by catalyzing the hydrolysis of arginine to ornithineand urea. Argininemia is an inherited autosomal recessive disorder characterized by a buildup of arginineand ammonia in the blood. Anti-Arginase-1 is highly specific for hepatocytes, and is therefore a sensitive andspecific marker of benign and malignant hepatic tumours
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Recombinant Human Arginase-1
- Clone: IHC400
- Conjugate: unconjugated
- Isotype: IgG2b
- Quantity: 1 mL
- Storage: store at 2-8°C
- Immunohistochemistry (IHC)