Anti-CD14 monoclonal antibody, clone TüK4 [R-PE]
Product Details
- Cat. No.
- CABT-45579MH
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Mouse Anti-Human CD14 monoclonal antibody for FC. Mouse anti human CD14 antibody, clone TüK4 recognizes the human CD14 cell surface antigen. CD14 is a 55 KDa glycoprotein that contains multiple leucin-rich repeats. It is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) linkage but a soluble form of CD14 also exists. CD14 is strongly expressed on the surface of monocytes and macrophages but has also been shown to be expressed on the surface of non-myeloid cells. CD14 functions as a pattern recognition receptor in innate immunity for a variety of ligands, in particular for the LPS (endotoxin) of Gram-negative bacteria. Mouse anti human CD14 antibody, clone TüK4 has been shown to block SDF-induced chemotaxis of U937 cells in a dose –dependent manner. Serotec recommend the use of the anti-human CD14 antibody, Low Endotoxin format for this purpose. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood. Applications：FC
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Bovine, Cat (Feline), Cynomolgus Monkey, Dog (Canine), Goat, Human, Llama, Mink, Pig (Swine), Rabbit (Lapine), Sheep (Ovine)
- Conjugate: R-PE
- Isotype: IgG2a
- Gene: 929
Handling
- Quantity: 100 Tests
- Storage: Prior to reconstitution store at +4°C. After reconstitution store at +4°C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)