Anti-CD209 monoclonal antibody, clone MR-1 [Biotin]
Product Details
- Cat. No.
- CABT-47377MH
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Mouse Anti-Human CD209 monoclonal antibody for FC. Mouse anti Human CD209 antibody, clone MR-1 recognizes human DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN), a 45kD C-type lectin that binds ICAM-3 also known as CD209. CD209 is primarily expressed on a population of immature dendritic cells in peripheral tissues and on immature myeloid monocyte-derived DCs in vitro. CD209 is involved in dendritic cell (DC) migration and the initial interaction between DCs and naive T lymphocytes. CD209 also binds HIV-1 gp120 and plays a key role in the dissemination of HIV-1 by DCs. Clone MR-1 is reported to partially block the functional activity of DC-SIGN. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells in 100ul. Applications:FC
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Conjugate: Biotin
- Isotype: IgG1
- Gene: 30835
Handling
- Quantity: 100 μg
- Storage: in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)