Product & ReviewsAntibodies

Anti-CD209A monoclonal antibody, clone ER-TR9 [Biotin]

Product Details

Cat. No.
CABT-47791RM
Type
Primary Antibody
Clonality
Monoclonal
Host
Rat
Creative Diagnostics

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Description

Rat anti-Mouse CD209A monoclonal antibody for FC. Rat anti Mouse Sign-R1 antibody, clone ER-TR9 recognizes mouse SIGN-R1, a C-type lectin that has been identified as a murine homologue of the human DC-SIGN related molecule, L-SIGN. Mouse SIGN-R1 is specifically expressed on marginal zone macrophages in the spleen, medullary and subcapsular sinus macrophages in the lymph nodes, and at lower levels on liver sinusoidal endothelial cells. SIGN-R1 has not been detected on murine dendritic cell populations. Like many C-type lectins, SIGN-R1 functions as a pathogen recognition receptor in vivo and plays an important role in defence against pathogens. Antibodies, produced by clone ER-TR9, are reported to block the uptake of neutral polysaccharides by macrophages. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells in 100ul. Applications:FC

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Mouse
  • Conjugate: Biotin
  • Isotype: IgM
  • Gene: 170786

Handling

  • Quantity: 100 μg
  • Storage: Store at +4°C or at -20o if preferred. This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.

Applications

  • Flow Cytometry (FC)
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