Anti-CD247 monoclonal antibody, clone G3 [FITC]
Product Details
- Cat. No.
- CABT-48910MH
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Mouse Anti-Human CD247 monoclonal antibody for FC. The T cell antigen receptor (TCR) consists of a ligand-specific alpha/beta heterodimer non-covalently associated with five invariant chains including the CD3 gamma/delta/eta and zeta subunits, all of which are required for efficient surface expression. T cell activation through the TCR induces cellular differentiation and/or proliferation and the production of lymphokines and cytokines. Both the CD3 and TCR zeta subunits are proposed to be responsible for the intracellular signal transduction events. A novel monoclonal antibody, named G3, has been developed that is specific for the TCR zeta chain subunit (CD247). The antibody is capable of precipitating both non-phosphorylated and tyrosine phosphorylated TCR zeta chain and may be used to detect TCR zeta expressing cells using flow cytometry on permeabilised cells. Flow Cytometry Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. Applications：FC
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Mouse
- Conjugate: FITC
- Isotype: IgG2a
- Gene: 919
Handling
- Quantity: 100 μg
- Storage: in frost-free freezers is not recommended. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)