Anti-CD28 monoclonal antibody, clone 37.51.1 [Biotin]
Product Details
- Cat. No.
- CABT-48075HM
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Hamster
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Description
Hamster Anti-Mouse CD28 monoclonal antibody for FC. Hamster anti Mouse CD28 antibody, clone 37.51.1 recognizes murine CD28, an 80kDa cell surface glycoprotein that is expressed by most thymocyte subsets and by peripheral T-cells. Studies show that CD28 expression on thymocytes and splenic T-cells can be upregulated upon activation. Murine CD28 acts as a co-stimulatory signal and may play an important role in regulating the immune response of T-cells. Hamster anti Mouse CD28 antibody, clone 37.51.1 has been reported to enhance cytokine production and T-cell proliferation in combination with TCR-mediated signals. Flow Cytometry Use 20ul of the suggested working dilution to label 106 cells in 100ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. Applications：FC
Biological Information
- Clonality: Monoclonal
- Host: Hamster
- Reactivity: Mouse
- Conjugate: Biotin
- Isotype: IgG
- Gene: 12487
Handling
- Quantity: 100 μg
- Storage: in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)