Product & ReviewsAntibodies

anti-CD33 / SIGLEC3 mouse monoclonal, 33-20, purified

Product Details

Cat. No.
691576
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
PROGEN

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Description

CD33 is a 67 kDa glycoprotein of the sialic acid-binding immunoglobulin-like lectin (SIGLEC) family, displaying the immune-receptor tyrosine-based inhibitory motif (ITIM), able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies. ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: stimulated human AML cells
  • Clone: 33-20
  • Conjugate: unconjugated
  • Isotype: IgG1 kappa

Handling

  • Quantity: 1 mL (100 µg/ml)
  • Storage: store at 2-8°C

Applications

  • Flow Cytometry (FC)
  • Immunocytochemistry (ICC)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
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Sensitivity rating
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