Product & ReviewsAntibodies

Anti-CD4 monoclonal antibody, clone RM4-5 [FITC]

Product Details

Cat. No.
CABT-45148RM
Type
Primary Antibody
Clonality
Monoclonal
Host
Rat
Creative Diagnostics

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Description

Rat Anti-Mouse CD4 monoclonal antibody for FC. Rat anti Mouse CD4 antibody, clone RM4-5 detects mouse CD4, a 55 kD protein also known as Ly-4 and L3T4. CD4 is a single chain transmembraneous glycoprotein which belongs to the immunoglobulin superfamily, and is primarily expressed on peripheral blood monocytes and tissue macrophages. CD4 is also expressed on a subpopulation of regulatory T cells (CD4+CD25+), which play a key role in the maintenance of self tolerance. Rat anti Mouse CD4 antibody, clone RM4-5 useful for in vitro blocking of ligand binding, as well as in vitro CD4+ T cell depletions. Flow Cytometry Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. Applications:FC

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Mouse
  • Conjugate: FITC
  • Isotype: IgG2a
  • Gene: 12504

Handling

  • Quantity: 100 μg
  • Storage: in frost-free freezers is not recommended. This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

Applications

  • Flow Cytometry (FC)
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