Product & ReviewsAntibodies
anti-CD41a mouse monoclonal, 96-2C1, purified
Product Details
- Cat. No.
- 691580
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
96-2C1 reacts with a calcium-dependent complex of CD41/CD61 (GPIIb/IIIa; integrin IIa/3), a dimer of 90 and 140 kDa, present on the membrane of normal platelets and megakaryocytes. This complex forms the receptor of fibrinogen, fibronectin and Von Willebrand factor, and mediates platelet adhesion and aggregation. MAbs to CD41a have been shown to have anti-proliferative effects on various lymphoid cell lines, particularly those derived from large cell lymphomas
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: stimulated human PBL
- Clone: 96-2C1
- Conjugate: unconjugated
- Isotype: IgG1 kappa
Handling
- Quantity: 1 mL (100 µg/ml)
- Storage: store at 2-8°C
Applications
- Flow Cytometry (FC)
- Immunocytochemistry (ICC)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)